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20 CS 786: Computational Genomics

Syllabus:
Learning Objectives:
Course Number 20 CS 786
Credit Hours 3 Graduate
Catalog Data
Computational problems and algorithms in genome analysis.
Textbooks Durbin, Biological Sequence Analysis, Cambridge, 1998.
References
Current Articles
Prerequisites by Topic
1. 20-CS-471, 671 or 20-CS-332, Design and Analysis of Algorithms
2. Programming
Goals
To expose the student to computational problems and current solutions in genome research.
Topics
1. Molecular biology basics
2. Sequence alignment
3. Clustering
4. Search for motifs
5. Machine learning methods
6. Graph-theoretic methods
7. Current software survey
Computer Usage
The Internet and computers are used for data retrieval and analysis.
Labs
1. Binding sites analysis
2. Expression data clustering
3. Protein structure prediction
Estimated ABET
Engineering Science: 1.8 credits or 60
Engineering Design: 1.2 credits or 40%
Prepared By Yizong Cheng., Ph.D. on 2002/09/01